Article
Involvement of a battery of investigated genes in lipid droplet pathophysiology and associated comorbidities.
Adipocyte - 1 Dec 2024
Al Harake Sami N, Abedin Yasamin, Hatoum Fatema, Nassar Nour Zahraa, Ali Ali, Nassar Aline, Kanaan Amjad, Bazzi Samer, Azar Sami, Harb Frederic, Ghadieh Hilda E
Abstract excerpt
Lipid droplets (LDs) are highly specialized energy storage organelles involved in the maintenance of lipid homoeostasis by regulating lipid flux within white adipose tissue (WAT). The physiological function of adipocytes and LDs can be compromised by mutations in several genes, leading to NEFA-induced lipotoxicity, which ultimately manifests as metabolic complications, predominantly in the form of dyslipidemia,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.