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Article

Genetic analysis of nitric oxide synthase 1 variants in schizophrenia and bipolar disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2010

Silberberg Gilad, Ben-Shachar Dorit, Navon Ruth

Abstract excerpt

Nitric oxide (NO) is a neurotransmitter that acts as a second messenger of the N-methyl-D-aspartate receptor and interacts with the dopaminergic and the serotonergic systems. NO involvement in pathological processes relevant to neuropsychiatric disorders stems from its ability to modulate certain forms of synaptic plasticity, and from its capacity to be transformed to a highly active free radical. Additionally,...

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Identifiers

PMID: 20645313
DOI: 10.1002/ajmg.b.31112

Genes

NOS1

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