Article
Evidence for association between the 5' flank of the NOS1 gene and schizophrenia in the Chinese population.
The international journal of neuropsychopharmacology - 1 Dec 2008
Tang Wei, Huang Ke, Tang Ruqi, Zhou Guoquan, Fang Chao, Zhang Jing, Du Lingzhen, Feng Guoying, He Lin, Shi Yongyong
Abstract excerpt
Nitric oxide (NO) plays an important role in the dopaminergic and serotonergic system as the second messenger of the NMDA receptor and has possible roles in neurotransmission, neurosecretion, synaptic plasticity, and tissue injury in many neurological disorders, including schizophrenia. There is also genetic evidence to support the human NOS1 (neuronal nitric oxide synthase 1) gene as a promising candidate gene...
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