Article
Deletion of the late cornified envelope genes, LCE3C and LCE3B, is associated with rheumatoid arthritis.
Arthritis and rheumatism - 1 May 2010
Docampo Elisa, Rabionet Raquel, Riveira-Muñoz Eva, Escaramís Georgia, Julià Antonio, Marsal Sara, Martín José Ezequiel, González-Gay Miguel Angel, Balsa Alejandro, Raya Enrique, Martín Javier, Estivill Xavier
Abstract excerpt
OBJECTIVE: The risk of rheumatoid arthritis (RA) is increased in the offspring of individuals affected with various autoimmune disorders, including psoriasis. Recently, the deletion of 2 genes from the late cornified envelope (LCE) gene cluster, LCE3C and LCE3B, has been associated with psoriasis in several populations. The purpose of this study was to assess whether this polymorphic gene deletion could also be...
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