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Article

Worldwide population distribution of the common LCE3C-LCE3B deletion associated with psoriasis and other autoimmune disorders.

BMC genomics - 17 Apr 2013

Bassaganyas Laia, Riveira-Muñoz Eva, García-Aragonés Manel, González Juan R, Cáceres Mario, Armengol Lluís, Estivill Xavier

Abstract excerpt

BACKGROUND: There is increasing evidence of the importance of copy number variants (CNV) in genetic diversity among individuals and populations, as well as in some common genetic diseases. We previously characterized a common 32-kb insertion/deletion variant of the PSORS4 locus at chromosome 1q21 that harbours the LCE3C and LCE3B genes. This variant allele (LCE3C_LCE3B-del) is common in patients with psoriasis...

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Identifiers

PMID: 23594316
DOI: 10.1186/1471-2164-14-261
PMCID: PMC3639927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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