Article
Genetic variability in noncoding RNAs: involvement of miRNAs and long noncoding RNAs in osteoporosis pathogenesis.
Epigenomics - 1 Nov 2020
Fittipaldi Simona, Visconti Virginia Veronica, Tarantino Umberto, Novelli Giuseppe, Botta Annalisa
Abstract excerpt
The pathogenesis of osteoporosis is multifactorial and is the consequence of genetic, hormonal and lifestyle factors. Epigenetics, including noncoding RNA (ncRNA) deregulation, represents a link between susceptibility to develop the disease and environmental influences. The majority of studies investigated the expression of ncRNAs in osteoporosis patients; however, very little information is available on their...
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