Article
[Status of gene mutation and copy number of EGFR in 290 cases of non-small cell lung carcinoma].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Oct 2008
Liang Zhi-Yong, Zeng Xuan, Zhang Jing, Wu Sha-Fei, Gao Jie, Liu Tong-Hua
Abstract excerpt
OBJECTIVE: To investigate EGFR mutations and gene copy number status in non-small cell lung carcinomas in the Chinese patients. METHODS: Using formalin fixed and paraffin embedded tissue samples, EGFR mutations were investigated in 290 cases of non-small cell lung carcinomas by microdissection and scorpions amplification refractory mutation system. The status of EGFR gene copy number was investigated by FISH....
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