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Article

Polymorphisms in the AR and PSA genes as markers of susceptibility and aggressiveness in prostate cancer.

Cancer investigation - 1 Nov 2010

Kuasne Hellen, Rodrigues Iara Sant'Ana, Fuganti Paulo Emílio, Losi-Guembarovski Roberta, Ito Kazuhiro, Kishima Marina O, Rodrigues Marco Aurélio de Freitas, Rogatto Silvia Regina, Santos Rodrigo Mattos dos, Cólus Ilce Mara de Syllos

Abstract excerpt

The study of genes involved in androgen pathway can contribute to a better knowledge of prostate cancer. Our aim was to examine if polymorphisms in prostate-specific antigen (PSA) and androgen receptor (AR) genes were involved in prostate cancer risk and aggressiveness. Genotypes were determined by PCR-RFLP (PSA) or using a 377 ABI DNA Sequencer (AR). PSA(G/G) genotype (OR = 1.78, 95% CI = 1.06–2.99) and AR short...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Restriction Fragment Length

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Share to Receptors, Androgen

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Identifiers

PMID: 20632874
DOI: 10.3109/07357907.2010.483509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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