Article
Polymorphic CAG repeats in the androgen receptor gene, prostate-specific antigen polymorphism and prostate cancer risk.
Carcinogenesis - 1 Oct 2002
Gsur Andrea, Preyer Martin, Haidinger Gerald, Zidek Thomas, Madersbacher Stephan, Schatzl Georg, Marberger Michael, Vutuc Christian, Micksche Michael
Abstract excerpt
As the development of prostate cancer is androgen-dependent, it has been hypothesized that variation in transcriptional activity by the androgen receptor (AR) related to polymorphic CAG repeats in exon 1, influences prostate cancer risk. The AR regulates gene transcription by binding to androgen-...
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