Article
Polymorphism in ARE-I region of prostate-specific antigen gene associated with low serum testosterone level and high-grade prostate cancer.
Urology - 1 Jun 2005
Schatzl Georg, Marberger Michael, Remzi Mesut, Grösser Petra, Unterlechner Julia, Haidinger Gerald, Zidek Thomas, Preyer Martin, Micksche Michael, Gsur Andrea
Abstract excerpt
OBJECTIVES: To examine the impact of polymorphism in the androgen-responsive element I region of the prostate-specific antigen (PSA) gene on the serum testosterone level and Gleason score in patients with newly diagnosed, untreated prostate cancer (PCa). High-grade PCa is associated with a low serum testosterone level, and the testosterone level has been negatively correlated with the expression of PSA. METHODS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
