Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between polymorphisms in sex hormones synthesis and metabolism and prostate cancer aggressiveness.

PloS one - 1 Jan 2017

Robles-Fernandez Inmaculada, Martinez-Gonzalez Luis Javier, Pascual-Geler Manrique, Cozar Jose Manuel, Puche-Sanz Ignacio, Serrano Maria Jose, Lorente Jose Antonio, Alvarez-Cubero Maria Jesus

Abstract excerpt

Novel biomarkers for prostate cancer (PCa) diagnosis and prognosis are necessary to improve the accuracy of current ones employed in clinic. We performed a retrospective study between the association of several polymorphisms in the main genes involved in the synthesis and metabolism of sex hormones and PCa risk and aggressiveness. A total of 311 Caucasian men (155 controls and 156 patients) were genotyped for 9...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to ESR2 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to LHCGR gene

Share to Gonadal Steroid Hormones

Share to Multigene Family

Share to Polymorphism, Single Nucleotide

Share to Prostatic Neoplasms

Share to Recurrence

Source

Open in PubMed Open full text

Identifiers

PMID: 28981526
DOI: 10.1371/journal.pone.0185447
PMCID: PMC5628818

Genes

ESR2
LHCGR
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between polymorphisms in sex hormones synthesis and metabolism and prostate cancer aggressiveness.PMID 28981526Read ↗

Molecular markers in key steroidogenic pathways, circulating steroid levels, and prostate cancer progression.Semantic proximity Read ↗

The impact of common genetic variations in genes of the sex hormone metabolic pathways on steroid hormone levels and prostate cancer aggressiveness.Semantic proximity Read ↗

Polymorphism in the Androgen Biosynthesis Gene (CYP17), a Risk for Prostate Cancer: A Meta-Analysis.Semantic proximity Read ↗

Role of hormonal genes and risk of prostate cancer: gene-gene interactions in a North Indian population.Semantic proximity Read ↗

CYP17 gene polymorphisms and prostate cancer risk: a meta-analysis based on 38 independent studies.Semantic proximity Read ↗

Genetic variations in genes involved in testosterone metabolism are associated with prostate cancer progression: A Spanish multicenter study.Semantic proximity Read ↗

Polymorphisms in androgen signaling pathway predisposing to prostate cancer.Semantic proximity Read ↗

Association of variants in estrogen-related pathway genes with prostate cancer risk.Semantic proximity Read ↗

Combination of polymorphisms from genes related to estrogen metabolism and risk of prostate cancers: the hidden face of estrogens.Semantic proximity Read ↗

Role of single nucleotide polymorphisms of the HSD3B1 gene (rs6203 and rs33937873) in the prediction of prostate cancer risk.Semantic proximity Read ↗

Estrogen receptors alpha (rs2234693 and rs9340799), and beta (rs4986938 and rs1256049) genes polymorphism in prostate cancer: evidence for association with risk and histopathological tumor characteristics in Iranian men.Semantic proximity Read ↗

Single and multigenic analysis of the association between variants in 12 steroid hormone metabolism genes and risk of prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.