Article
Association between estrogen and androgen receptor genes and prostate cancer risk.
European journal of endocrinology - 1 Jan 2009
Nicolaiew Nathalie, Cancel-Tassin Geraldine, Azzouzi Abdel Rahmene, Grand Beatrice Le, Mangin Philippe, Cormier Luc, Fournier Georges, Giordanella Jean-Pierre, Pouchard Michel, Escary Jean-Louis, Valeri Antoine, Cussenot Olivier
Abstract excerpt
OBJECTIVE: Prostate cancer (PC) is one of the principal causes of death among men. Steroid hormones are involved in normal prostate growth and carcinogenesis. The purpose of our study was to investigate the effects on PC risk of polymorphisms from three steroid hormone receptor genes: the androgen (AR), and the alpha (ESR1) and beta (ESR2) estrogen receptors. DESIGN AND METHODS: The study was performed on a...
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