Article
CARD15 mutations and perianal fistulating Crohn's disease: correlation and predictive value of antibiotic response.
Digestive diseases and sciences - 1 Mar 2011
Freire Paulo, Portela Francisco, Donato Maria M, Ferreira Manuela, Andrade Paulo, Sofia Carlos
Abstract excerpt
BACKGROUND: CARD15 mutations alter bowel immunity and increase susceptibility to Crohn's disease (CD). However, the relation between these mutations and Crohn's perianal fistulas has not been fully clarified. AIMS: To assess whether CARD15 mutations are associated with risk of developing Crohn's perianal fistulas and whether these mutations are predictors of the response of perianal fistulas to antibiotics....
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