Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Three common CARD15 mutations are not responsible for the pathogenesis of Crohn's disease in Iranians.

Hepato-gastroenterology - 1 Jan 2000

Teimoori-Toolabi Ladan, Vahedi Homayoun, Mollahajian Hamid, Kamali Esmat, Hajizadeh-Sikaroodi Shohreh, Zeinali Sirous, Tabrizian Tahmineh, Olfati Golrokh, Rashtak Shahrooz, Malekzadeh Fatemeh, Ghoddosi Alireza, Malekzadeh Reza

Abstract excerpt

BACKGROUND/AIMS: Crohn's disease frequency has increased in recent years in Iran. Genetic and environmental factors predispose people to this disease. Mutation in Caspase Recruitment Domain 15 (CARD15) gene is the most well known genetic predisposing factor to this disease. Frequency of three common CARD15 mutations has been studied in different ethnic groups. We aimed to study the frequency of these mutations in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Crohn Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Genetic Predisposition to Disease

Share to Nod2 Signaling Adaptor Protein

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 20583427

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Three common CARD15 mutations are not responsible for the pathogenesis of Crohn's disease in Iranians.PMID 20583427Read ↗

Frequency of three common mutations of CARD15/NOD2 gene in Iranian IBD patients.Semantic proximity Read ↗

CARD15 gene polymorphisms in Serbian patients with Crohn's disease: genotype-phenotype analysis.Semantic proximity Read ↗

NOD2/CARD15 mutations in Polish and Bosnian populations with and without Crohn's disease: prevalence and genotype-phenotype analysis.Semantic proximity Read ↗

Analysis of the three common mutations in the CARD15 gene (R702W, G908R and 1007fs) in South African colored patients with inflammatory bowel disease.Semantic proximity Read ↗

NOD2/CARD15 mutations in Croatian patients with Crohn's disease: prevalence and genotype-phenotype relationship.Semantic proximity Read ↗

CARD15 in inflammatory bowel disease and Crohn's disease phenotypes: an association study and pooled analysis.Semantic proximity Read ↗

NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe?Semantic proximity Read ↗

1007fs, G908R, R702W mutations and P268S, IVS8+158 polymorphisms of the CARD15 gene in Turkish inflammatory bowel disease patients and their relationship with disease-related surgery.Semantic proximity Read ↗

Distribution of common CARD15 variants in patients with sporadic Crohn's disease: cases from Turkey.Semantic proximity Read ↗

CARD15/NOD2 gene variants are associated with familially occurring and complicated forms of Crohn's disease.Semantic proximity Read ↗

[CARD15 mutations are poorly related to Crohn's disease phenotypes in Asturias].Semantic proximity Read ↗

Mutations in CARD15 and smoking confer susceptibility to Crohn's disease in the Danish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.