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Article

The potential of knockout mouse lines in defining the role of flavin-containing monooxygenases in drug metabolism.

Expert opinion on drug metabolism & toxicology - 1 Sept 2010

Shephard Elizabeth A, Phillips Ian R

Abstract excerpt

IMPORTANCE OF THE FIELD: Flavin-containing monooxygenases (FMOs) metabolize a number of therapeutic drugs. However, their role in drug metabolism has been overlooked compared with that of the cytochromes P450 (CYPs). Genetic variants of FMOs are expected to influence drug response and/or contribu...

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Share to Cytochrome P-450 Enzyme System
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20629583
DOI: 10.1517/17425255.2010.503705

Genes

FMO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20629583-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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