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Article

Involvement of DNA polymerase beta in repairing oxidative damages induced by antitumor drug adriamycin.

Toxicology and applied pharmacology - 1 Aug 2010

Liu Shukun, Wu Mei, Zhang Zunzhen

Abstract excerpt

Adriamycin (ADM) is a widely used antineoplastic drug. However, the increasing cellular resistance has become a serious limitation to ADM clinical application. The most important mechanism related to ADM-induced cell death is oxidative DNA damage mediated by reactive oxygen species (ROS). Base ex...

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Source

Identifiers

PMID: 20510258
DOI: 10.1016/j.taap.2010.05.011

Genes

ADM
SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20510258-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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