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Article

IL1RN VNTR and IL2-330 polymorphic genes are independently associated with chronic immune thrombocytopenia.

British journal of haematology - 1 Sept 2010

Rocha Andreia Maria Camargos, De Souza Cláudia, Rocha Gifone Aguiar, De Melo Fabrício Freire, Saraiva Isadora Sofia Borges, Clementino Nelma Cristina Diogo, Marino Marília Campos Abreu, Queiroz Dulciene Maria Magalhães

Abstract excerpt

Chronic Immune Thrombocytopenia (cITP) is an acquired immune-mediated disease associated with a T-helper cell type 1 (Th1) immune polarization, whose genetic risk factors, however, are largely unknown. We investigated polymorphisms in promoter regions of genes that code molecules involved in proi...

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Source

Identifiers

PMID: 20626741
DOI: 10.1111/j.1365-2141.2010.08318.x

Genes

TLR2
TLR4
TLR5
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20626741-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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