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Article

The -A162G polymorphism of the PON1 gene and the risk of sporadic amyotrophic lateral sclerosis.

Neurologia i neurochirurgia polska - 1 Jan 2000

Zawiślak Dorota, Ostrowska Monika, Golenia Aleksandra, Marona Monika, Tomik Barbara, Wołkow Paweł, Gryz-Kurek Elzbieta, Szczudlik Andrzej, Słowik Agnieszka

Abstract excerpt

BACKGROUND AND PURPOSE: Sporadic amyotrophic lateral sclerosis (sALS) is a devastating neurodegenerative disease, which results from complex genetic and environmental interactions. Recent studies have reported an association between several polymorphisms of the PON1 and PON2 genes and risk of sALS. The aim of the present study was to identify an association between the -A162G polymorphism of the promoter region...

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Identifiers

PMID: 20625960
DOI: 10.1016/s0028-3843(14)60038-4

Genes

PON1
PON2

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