Article
A strong association between VEGF-A rs28357093 and amyotrophic lateral sclerosis: a brazilian genetic study.
Molecular biology reports - 1 Sept 2022
da Costa Caroline Christine Pincela, de Lima Nayane Soares, da Cruz Pereira Bento Dhiogo, da Silva Santos Rodrigo, da Silva Reis Angela Adamski
Abstract excerpt
BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is a rare neurodegenerative disease that affects motor neurons and promotes progressive muscle atrophy. Vascular Endothelial Growth Factor A (VEGF-A) plays multiple roles in the central nervous systems (CNS). The purpose of this study was to evaluate the association between single nucleotide polymorphism (SNP) VEGF-A rs28357093 and ALS. METHODS AND RESULTS: This...
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