Article
IL-10 and TNFalpha genotypes in SLE.
Journal of biomedicine & biotechnology - 1 Jan 2010
López Patricia, Gutiérrez Carmen, Suárez Ana
Abstract excerpt
The production of two regulators of the inflammatory response, interleukin 10 (IL-10) and tumor necrosis factor alpha (TNFalpha), has been found to be deeply deregulated in SLE patients, suggesting that these cytokines may be involved in the pathogenesis of the disease. Genetic polymorphisms at the promoter regions of IL-10 and TNFalpha genes have been associated with different constitutive and induced cytokine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
