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Article

The Impact of the IL-10 Gene Polymorphism on mRNA Expression and IL-10 Serum Concentration in Polish Lupus Patients.

International journal of molecular sciences - 18 May 2024

Żak-Gołąb Agnieszka, Cieślik Paweł, Siekiera Urszula, Kuśmierz Dariusz, Hrycek Antoni, Holecki Michał

Abstract excerpt

Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the production of autoantibodies against a lot of nuclear components. Despite many studies on the genetic background of this disease, the pathogenesis remains unclear. The aim of the study is to comprehensively evaluate the polymorphism of the IL-10 promoter gene, its mRNA expression, and the serum IL-10 concentration of SLE...

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Identifiers

PMID: 38791549
DOI: 10.3390/ijms25105511
PMCID: PMC11122543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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