Article
IL-10 and TNF-alpha promoter polymorphisms in susceptibility to systemic lupus erythematosus in Taiwan.
Clinical and experimental rheumatology - 1 Jan 2000
Lin Ying-Ju, Wan Lei, Huang C-M, Sheu J J-C, Chen S-Y, Lin T-H, Chen D-Y, Hsueh K-C, Lai C-C, Tsai F-J
Abstract excerpt
OBJECTIVES: The genetic control of Interleukin-10 (IL-10) and Tumour necrosis factor-alpha (TNF-alpha) production and the possible interaction between the two cytokines in influencing SLE susceptibility as well as clinical features has not been completely evaluated in the Taiwanese population. METHODS: We investigated the association of IL-10 and TNF-alpha promoter polymorphisms (-1082, -819 and -592 for IL-10...
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