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Article

Can intra-Y gene conversion oppose the degeneration of the human Y chromosome? A simulation study.

Genome biology and evolution - 12 Jul 2010

Marais Gabriel A B, Campos Paulo R A, Gordo Isabel

Abstract excerpt

The human Y is a genetically degenerate chromosome, which has lost about 97% of the genes originally present. Most of the remaining human Y genes are in large duplicated segments (ampliconic regions) undergoing intense Y-Y gene conversion. It has been suggested that Y-Y gene conversion may help these genes getting rid of deleterious mutations that would inactivate them otherwise. Here, we tested this idea by...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 20624739
DOI: 10.1093/gbe/evq026
PMCID: PMC2997549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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