Article
Positive and negative selection on mammalian Y chromosomes.
Molecular biology and evolution - 1 Jun 2005
Gerrard Dave T, Filatov Dmitry A
Abstract excerpt
Y chromosomes are genetically degenerate in most organisms studied. The loss of genes from Y chromosomes is thought to be due to the inefficiency of purifying selection in nonrecombining regions, which leads to the accumulation of deleterious mutations via the processes of hitchhiking, background selection, and Muller's ratchet. As the severity of these processes depends on the number of functional genes linked...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.