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New insights into the evolution of human Y chromosome palindromes through mutation and gene conversion.

Human molecular genetics - 16 Nov 2021

Bonito Maria, D'Atanasio Eugenia, Ravasini Francesco, Cariati Selene, Finocchio Andrea, Novelletto Andrea, Trombetta Beniamino, Cruciani Fulvio

Abstract excerpt

About one-quarter of the euchromatic portion of the male-specific region of the human Y chromosome consists of large duplicated sequences that are organized in eight palindromes (termed P1-P8), which undergo arm-to arm gene conversion, a proposed mechanism for maintaining their sequence integrity. Although the relevance of gene conversion in the evolution of palindromic sequences has been profoundly recognized,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34244762
DOI: 10.1093/hmg/ddab189
PMCID: PMC8600007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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