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Article

Gene loss on Y chromosomes: a consequence of purifying selection?

Fly - 1 Jan 2000

Kaiser Vera B

Abstract excerpt

Recombination restriction between evolving sex chromosomes leads to the degeneration of the chromosome that is present only in the heterogametic sex (the Y chromosome in XY species). The evolutionary forces driving Y chromosome degeneration, however, are still under debate and include positive and negative selection models. In a recent study, we showed that the rate of accumulation of loss-of-function mutations...

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PMID: 20657178
DOI: 10.4161/fly.4.4.12669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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