Article
Disclosing complex mutational dynamics at a Y chromosome palindrome evolving through intra- and inter-chromosomal gene conversion.
Human molecular genetics - 1 Jan 2023
Bonito Maria, Ravasini Francesco, Novelletto Andrea, D'Atanasio Eugenia, Cruciani Fulvio, Trombetta Beniamino
Abstract excerpt
The human MSY ampliconic region is mainly composed of large duplicated sequences that are organized in eight palindromes (termed P1-P8), and may undergo arm-to-arm gene conversion. Although the importance of these elements is widely recognized, their evolutionary dynamics are still nuanced. Here, we focused on the P8 palindrome, which shows a complex evolutionary history, being involved in intra- and...
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