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Article

Roles of Bcl-3 in the pathogenesis of murine type 1 diabetes.

Diabetes - 1 Oct 2010

Ruan Qingguo, Zheng Shi-Jun, Palmer Scott, Carmody Ruaidhri J, Chen Youhai H

Abstract excerpt

OBJECTIVE: It has long been recognized that autoimmunity is often associated with immunodeficiency. The mechanism underlying this paradox is not well understood. Bcl-3 (B-cell lymphoma 3) is an atypical member of the IκB (inhibitor of the nuclear factor-κB) family that is required for lymphoid organogenesis and germinal center responses. Mice deficient in Bcl-3 are immunodeficient because of the...

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Identifiers

PMID: 20622172
DOI: 10.2337/db10-0480
PMCID: PMC3279524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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