Article
Identification of the oxidative stress-related gene MSRA as a rheumatoid arthritis susceptibility locus by genome-wide pathway analysis.
Arthritis and rheumatism - 1 Nov 2010
Martín Jose-Ezequiel, Alizadeh Behrooz Z, González-Gay Miguel A, Balsa Alejandro, Pascual-Salcedo Dora, Fernández-Gutiérrez Benjamín, Raya Enrique, Franke Lude, van't Slot Ruben, Coenen Marieke J H, van Riel Piet, Radstake Timothy R D J, Koeleman Bobby P C, Martín Javier
Abstract excerpt
OBJECTIVE: Genome-wide association studies carried out in rheumatoid arthritis (RA) have led to the discovery of several genetic associations with this disease. Still, the current associated genetic variations can explain only part of the genetic risk involved in RA, and it is well recognized that these genome-wide association studies are likely underpowered to detect all common disease variants. This study was...
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