Article
Sumoylation of Drosophila transcription factor STAT92E.
Journal of innate immunity - 1 Jan 2010
Grönholm Juha, Ungureanu Daniela, Vanhatupa Sari, Rämet Mika, Silvennoinen Olli
Abstract excerpt
STAT92E is an essential transcription factor in Drosophila melanogaster for the development of several organs and the immune system. The JAK/STAT pathway employs different evolutionary conserved regulatory mechanisms to control biological processes. Numerous transcription factors in both mammals and invertebrates have been shown to be either activated or inhibited by a covalent modification with a small...
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