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Article

Performance and clinical evaluation of a sensitive multiplex assay for the rapid detection of common NPM1 mutations.

The Journal of molecular diagnostics : JMD - 1 Sept 2010

Hafez Michael, Ye Fei, Jackson Keith, Yang Zhe, Karp Judith E, Labourier Emmanuel, Gocke Christopher D

Abstract excerpt

Determination of NPM1 mutation status has become essential for the molecular classification of acute myeloid leukemias (AML). Methods with high clinical sensitivity and specificity adapted to the molecular laboratory workflow are required for the diagnosis, prognosis, and monitoring of AML with normal karyotype. We report here the development and evaluation of a novel, streamlined, RNA-based assay for the rapid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20616361
DOI: 10.2353/jmoldx.2010.090219
PMCID: PMC2928427

Genes

NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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