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Clinical Laboratory Validation and Implementation of Quantitative, Real-Time PCR-based Monitoring of NPM1 Type A Mutation

2019-10-29

Abstract excerpt

<h4>ABSTRACT</h4> NPM1 is frequently mutated in acute myeloid leukemia (AML) and the mutations consist of a variety of small insertions; the most common NPM1 mutation (ie, Type A) accounts for approximately 80% of all NPM1 mutations. NPM1 mutations have been reported to have prognostic significance in AML and, more recently, monitoring mutant NPM1 levels during and after therapy has been described to predict rela...

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Literature Corpus work
8b3434c6-11da-5701-99ad-2be7f8c647b3
DOI
10.1101/19010124
Open publication

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Clinical Laboratory Validation and Implementation of Quantitative, Real-Time PCR-based Monitoring of NPM1 Type A MutationDOI 10.1101/19010124
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