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Article

CDC 25A gene 263C/T, -350C/T, and -51C/G polymorphisms in breast carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2010

Karagoz Isik Didem, Ozaslan Mehmet, Cengiz Beyhan, Kalender Mehmet Emin, Kilic Ibrahim Halil, Oztuzcu Serdar, Gogebakan Bulent, Demiryurek Abdullah Tuncay

Abstract excerpt

The family of cell division cycle 25 (CDC25) phosphatase is one of the important regulators of the cell cycle progression. In mammalian cells, three isoforms have been identified: CDC25A, CDC25B, and CDC25C. CDC25A is required to enter S time, and the overexpression of this phosphatase accelerates the entrance to S time. CDC25A overexpression could render tumor cells less sensitive to DNA replication checkpoints,...

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Identifiers

PMID: 20614206
DOI: 10.1007/s13277-010-0075-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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