Article
Membranes of high- and low-metastatic L tumor cell variants.
Invasion & metastasis - 1 Jan 1991
Kier A B, Franklin C
Abstract excerpt
A model system of metastasis, L-929 fibroblasts and a derivative cell line, A-9 cells, was developed in order to compare the membrane properties of high- and low-metastatic cells cultured in chemically defined medium. The metastatic ability of L-929 and A-9 cells in athymic (nude) mice was examined. Both cell lines produced local tumors, but only L-929 fibroblasts metastasized to the lung. The plasma membranes of...
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