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Bilayer Forming Phospholipids as Targets for Cancer Therapy

9 May 2022

Abstract excerpt

Phospholipids represent a crucial component for the structure of cell membranes. Phosphatidylcholine and phosphatidylethanolamine are two phospholipids that comprise the majority of cell membranes. De novo biosynthesis of phosphatidylcholine and phosphatidylethanolamine occurs via the Kennedy pathway, and perturbations in the regulation of this pathway are linked to a variety of human diseases, including cancer....

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PMID: 35563655
DOI: 10.3390/ijms23095266

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