Article
Modulation of membrane phenotype, matrix adhesion and microinvasiveness of metastatic tumour cells by HUdR.
Cell biochemistry and function - 1 Oct 1990
Timár J, Pogány G, Balázs M, Szöllösi J, Ladányi A, Oláh J, Timár F, Lapis K, Jeney A
Abstract excerpt
The effect of HUdR, proved to be anti-metastatic in vivo, was studied in vitro on cell proliferation, nucleoside uptake, membrane fluidity, expression of galactosylated glycans and proteoglycans in metastatic HM tumour cells. The observed increase in membrane fluidity and the suppression of nucle...
Topics
- Animals
- Antigens, Surface
- Antimetabolites, Antineoplastic
- Cell Adhesion
- Cell Division
- Cell Membrane
- Deoxyuridine
- Extracellular Matrix
- Glycoconjugates
- Humans
- Membrane Fluidity
- Neoplasm Invasiveness
- Neoplasms, Experimental
- Nucleosides
- Phenotype
- Proteoglycans
- Tritium