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Article

Failure to find an association between CD14-159C/T polymorphism and asthma: a family-based association test and meta-analysis.

Allergology international : official journal of the Japanese Society of Allergology - 1 Mar 2006

Nishimura Fumichika, Shibasaki Masanao, Ichikawa Kunio, Arinami Tadao, Noguchi Emiko

Abstract excerpt

BACKGROUND: CD14 is an essential component of the receptor for lipopolysaccharide (LPS). LPS stimulates T-helper type 1 (Th1) cytokine expression, potentially suppressing Th2 immune responses involved in IgE-mediated allergic diseases. Previous studies have reported that -159C/T, a promoter polym...

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Identifiers

PMID: 17075287
DOI: 10.2332/allergolint.55.55

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17075287-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Failure to find an association between CD14-159C/T polymorphism and asthma: a family-based association test and meta-analysis.PMID 17075287Read ↗

No Association Between -159C/T Polymorphism of the CD14 Gene and Asthma Risk: a Meta-Analysis of 36 Case-Control Studies.Semantic proximity Read ↗

The -159C/T polymorphism in the CD14 gene and the risk of asthma: a meta-analysis.Semantic proximity Read ↗

The CD14 C-159T polymorphism is not associated with asthma or asthma severity in an Australian adult population.Semantic proximity Read ↗

Association of CD14 -159 (-260C/T) polymorphism and asthma risk: an updated genetic meta-analysis study.Semantic proximity Read ↗

Evaluation of the CD14 C-159 T polymorphism in the German Multicenter Allergy Study cohort.Semantic proximity Read ↗

The C-159T polymorphism in the CD14 promoter is associated with serum total IgE concentration in atopic Chinese children.Semantic proximity Read ↗

Association of CD14 gene -159C/T polymorphism with allergic rhinitis risk: a meta-analysis.Semantic proximity Read ↗

Association of CD14 C159T polymorphism with atopic asthma susceptibility in children from Southeastern China: a case-control study.Semantic proximity Read ↗

The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma.Semantic proximity Read ↗

CD14 gene polymorphism is not associated with asthma but rather with bronchial obstruction and hyperreactivity in Slovenian children with non-atopic asthma.Semantic proximity Read ↗

Association of CD14 -260 (-159) C>T and asthma: a systematic review and meta-analysis.Semantic proximity Read ↗

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