Article
The C-159T polymorphism in the CD14 promoter is associated with serum total IgE concentration in atopic Chinese children.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Aug 2003
Leung Ting Fan, Tang Nelson L S, Sung Ying Man, Li Albert M, Wong Gary W K, Chan Iris H S, Lam Christopher W K
Abstract excerpt
Activation of macrophages through CD14 by microbes is crucial in inducing immunity by type 1 T helper cells. A C-to-T polymorphism at position -159 of CD14 was associated with serum total IgE level in Caucasians but not in Japanese subjects. The objective of this study is to determine whether thi...
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