Article
Association between the CDC6 G1321A polymorphism and the risk of cervical cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jul 2010
Xiong Xing-Dong, Zeng Li-Qin, Xiong Qing-Yuan, Lu Sheng-Xiang, Zhang Zhi-Zhen, Luo Xi-Ping, Liu Xin-Guang
Abstract excerpt
INTRODUCTION: Cell division cycle protein 6 (CDC6) plays critical roles in DNA replication and carcinogenesis. The biological significance of the CDC6 G1321A polymorphism (V441I, rs13706) on cervical carcinogenesis is still unknown. Here, we examined the potential influence of this polymorphism on cell proliferation and the individual's susceptibility to cervical cancer. METHODS: We genotyped the CDC6 G1321A...
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