Article
Single nucleotide polymorphisms in PDCD6 gene are associated with the development of cervical squamous cell carcinoma.
Familial cancer - 1 Mar 2015
Zhou Bin, Bai Peng, Xue Hui, Zhang Zhu, Shi Shaoqing, Zhang Kui, Wang Yanyun, Wang Kana, Quan Yi, Song Yaping, Zhang Lin
Abstract excerpt
The programmed cell death 6 (PDCD6), discovered as a proapoptotic calcium-binding protein, has recently been found dysregulated in tumors of various origin and contributed to cancer cell viability. The aim of this study was to determine whether SNPs in PDCD6 are associated with cervical squamous cell carcinoma (CSCC). Polymerase chain reaction-restriction fragment length polymorphism method was used to genotype...
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