Article
Increased risk of cervical cancer associated with cyclin D1 gene A870G polymorphism.
Cancer genetics and cytogenetics - 1 Jul 2005
Catarino Raquel, Matos Ana, Pinto Daniela, Pereira Deolinda, Craveiro Rogéria, Vasconcelos André, Lopes Carlos, Medeiros Rui
Abstract excerpt
Human papillomavirus (HPV) plays a major role in the etiology of cervical cancer. However, a complex correlation between viral and cellular genes is necessary for cell cycle control deregulation in the progression to invasive cervical cancer (ICC). Cyclin D1 (CCND1) is an important positive regul...
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