Article
Association analysis between the Cdc6 G1321A polymorphism and the risk for non-Hodgkin lymphoma and hepatocellular carcinoma.
Mutation research - 9 Mar 2009
Xiong Xing-Dong, Qiu Fu-En, Fang Jian-Hong, Shen Yi, Liang Chun, Jiang Wenqi, Zhuang Shi-Mei
Abstract excerpt
Cdc6 play crucial roles in DNA replication and carcinogenesis. The biological significance of the Cdc6 G1321A polymorphism (V441I, rs13706) is still not elucidated. Here we examined the influence of this polymorphism on the function of Cdc6 and the individual's susceptibility to non-Hodgkin lymphoma (NHL) and hepatocellular carcinoma (HCC). Unconditional logistic regression analysis revealed that the risk for NHL...
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