Article
The MBD4 Glu346Lys polymorphism is associated with the risk of cervical cancer in a Chinese population.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Nov 2012
Xiong Xing-Dong, Luo Xi-Ping, Liu Xinguang, Jing Xia, Zeng Li-Qin, Lei Ming, Hong Xiao-Shan, Chen Yu
Abstract excerpt
OBJECTIVE: Methyl-CpG binding domain 4 (MBD4) protein functions as a DNA repair enzyme and plays an important role in maintaining genome integrity and carcinogenesis. The polymorphisms in the MBD4 gene may be associated with differences in DNA repair capacity and thereby influence an individual's susceptibility to cervical cancer. To verify this hypothesis, we examined the potential association between the MBD4...
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