CCND1 rs9344 polymorphisms are associated with the genetic susceptibility to cervical cancer in Chinese population.

doi:10.1002/mc.20801

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Article

CCND1 rs9344 polymorphisms are associated with the genetic susceptibility to cervical cancer in Chinese population.

Molecular carcinogenesis - 1 Feb 2012

Wang Ning, Qian Xiuyan, Wang Shizhuo, Gao Hong, Wang Lili, Huo Yunlong, Zhang Shulan

Abstract excerpt

Cyclin D1, with a common G/A polymorphism in rs9344, is an essential regulator of the G1 phase in cell cycles and plays an important role in several tumor types, and the homology of cyclin D1 with human papillomavirus (HPV)-16 E7 brought our attention to CCND1 gene in cervical cancer. A total of 738 native Chinese subjects consist of 327 cases and 411 controls were enrolled in this study. CCND1 genotyping was...

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PMID: 21594903
DOI: 10.1002/mc.20801

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CCND1

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