Article
Kip3, the yeast kinesin-8, is required for clustering of kinetochores at metaphase.
Cell cycle (Georgetown, Tex.) - 1 Jul 2010
Wargacki Megan M, Tay Jessica C, Muller Eric G, Asbury Charles L, Davis Trisha N
Abstract excerpt
In Saccharomyces cerevisiae, chromosome congression clusters kinetochores on either side of the spindle equator at metaphase. Many organisms require one or more kinesin-8 molecular motors to achieve chromosome alignment. The yeast kinesin-8, Kip3, has been well studied in vitro but a role in chromosome congression has not been reported. We investigated Kip3's role in this process using semi-automated,...
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