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Article

Structural studies of mutant forms of the PQQ-forming enzyme PqqC in the presence of product and substrate.

Proteins - 15 Aug 2010

Puehringer Sandra, RoseFigura Jordan, Metlitzky Moritz, Toyama Hirohide, Klinman Judith P, Schwarzenbacher Robert

Abstract excerpt

Pyrroloquinoline quinone [4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid (PQQ)] is a bacterial cofactor in numerous alcohol dehydrogenases including methanol dehydrogenase and glucose dehydrogenase. Its biosynthesis in Klebsiella pneumoniae is facilitated by six genes, pqqABCDEF and proceeds by an unknown pathway. PqqC is one of two metal free oxidases of known structure and catalyzes...

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PMID: 20602352
DOI: 10.1002/prot.22769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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