Article
Exploring the ubiquinone binding cavity of respiratory complex I.
The Journal of biological chemistry - 5 Oct 2007
Tocilescu Maja A, Fendel Uta, Zwicker Klaus, Kerscher Stefan, Brandt Ulrich
Abstract excerpt
Proton pumping respiratory complex I is a major player in mitochondrial energy conversion. Yet little is known about the molecular mechanism of this large membrane protein complex. Understanding the details of ubiquinone reduction will be prerequisite for elucidating this mechanism. Based on a recently published partial structure of the bacterial enzyme, we scanned the proposed ubiquinone binding cavity of...
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