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Article

Genetic, epigenetic, and gene-by-diet interaction effects underlie variation in serum lipids in a LG/JxSM/J murine model.

Journal of lipid research - 1 Oct 2010

Lawson Heather A, Zelle Kathleen M, Fawcett Gloria L, Wang Bing, Pletscher L Susan, Maxwell Taylor J, Ehrich Thomas H, Kenney-Hunt Jane P, Wolf Jason B, Semenkovich Clay F, Cheverud James M

Abstract excerpt

Variation in serum cholesterol, free-fatty acids, and triglycerides is associated with cardiovascular disease (CVD) risk factors. There is great interest in characterizing the underlying genetic architecture of these risk factors, because they vary greatly within and among human populations and between the sexes. We present results of a genome-wide scan for quantitative trait loci (QTL) affecting serum...

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Cardiovascular Diseases
Crosses, Genetic
Diet
Epigenesis, Genetic
Lipids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quantitative Trait Loci

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PMID: 20601649
DOI: 10.1194/jlr.M006957
PMCID: PMC2936764

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