Article
Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity.
PLoS genetics - 1 Feb 2006
Wang Susanna, Yehya Nadir, Schadt Eric E, Wang Hui, Drake Thomas A, Lusis Aldons J
Abstract excerpt
The integration of expression profiling with linkage analysis has increasingly been used to identify genes underlying complex phenotypes. The effects of gender on the regulation of many physiological traits are well documented; however, "genetical genomic" analyses have not yet addressed the degree to which their conclusions are affected by sex. We constructed and densely genotyped a large F2 intercross derived...
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