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Article

Endogenous H2O2 produced by Streptococcus pneumoniae controls FabF activity.

Biochimica et biophysica acta - 1 Sept 2010

Benisty Rachel, Cohen Aharon Yehonatan, Feldman Alexandra, Cohen Zvi, Porat Nurith

Abstract excerpt

FabF elongation condensing enzyme is a critical factor in determining the spectrum of products produced by the FASII pathway. Its active site contains a critical cysteine-thiol residue, which is a plausible target for oxidation by H2O2. Streptococcus pneumoniae produces exceptionally high levels of H2O2, mainly through the conversion of pyruvate to acetyl-P via pyruvate oxidase (SpxB). We present evidence showing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20601114
DOI: 10.1016/j.bbalip.2010.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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